What causes carpal tunnel syndrome?
Usually the cause is unknown. Pressure on the nerve can happen
several ways: swelling of the lining of the flexor tendons, called
tenosynovitis; joint dislocations, fractures, and arthritis can narrow the
tunnel; and keeping the wrist bent for long periods of time. Fluid retention
during pregnancy can cause swelling in the tunnel and symptoms of carpal
tunnel syndrome, which often go away after delivery. Thyroid conditions,
rheumatoid arthritis, and diabetes also can be associated with carpal tunnel
syndrome. There may be a combination of causes.
Signs and symptoms of carpal tunnel syndrome
Carpal tunnel syndrome symptoms usually include pain, numbness,
tingling, or a combination of the three. The numbness or tingling most often
takes place in the thumb, index, middle, and ring fingers. The symptoms
usually are felt during the night but also may be noticed during daily
activities such as driving or reading a newspaper. Patients may sometimes
notice a weaker grip, occasional clumsiness, and a tendency to drop things.
In severe cases, sensation may be permanently lost and the muscles at the
base of the thumb slowly shrink (thenaratrophy), causing difficulty with
pinch.
Diagnosis of carpal tunnel syndrome
A detailed history including medical conditions, how the hands have
been used, and whether there were any prior injuries is important. An x-ray
may be taken to check for the other causes of the complaints such as
arthritis or a fracture. In some cases, laboratory tests may be done if
there is a suspected medical condition that is associated with CTS. A nerve
conduction study (NCV) and/or electromyogram (EMG) may be done to confirm
the diagnosis of carpal tunnel syndrome as well as to check for other
possible nerve problems.
Treatment of carpal tunnel syndrome
Symptoms may often be relieved without surgery. Identifying and treating
medical conditions, changing the patterns of hand use, or keeping the wrist
splinted in a straight position may help reduce pressure on the nerve.
Wearing wrist splints at night may relieve the symptoms that interfere with
sleep. A steroid injection into the carpal tunnel may help relieve the
symptoms by reducing swelling around the nerve.
When symptoms are severe or do not improve, surgery may be needed to make more room for the nerve. Pressure on the nerve is decreased by cutting the ligament that forms the roof (top) of the tunnel on the palm side of the hand (see Figure 3). Incisions for this surgery may vary, but the goal is the same: to enlarge the tunnel and decrease pressure on the nerve. Following surgery, soreness around the incision may last for several weeks or months. The numbness and tingling may disappear quickly or slowly. It may take several months for strength in the hand and wrist to return to normal. Carpal tunnel symptoms may not completely go away after surgery, especially in severe cases.

Figure 1: The carpal tunnel is found at the base of the palm. It is formed by the bones of the wrist and the transverse carpal ligament. Increased pressure in the tunnel affects the function of the median nerve.

Figure 2: Aspects of median nerve function.

Figure 3: The goal of surgery is to free the ligament
to allow more room for the median nerve in the carpal tunnel.
© 2006 American Society for Surgery of the Hand. Developed by the ASSH
Public Education Committee.
Adapted/modified/altered from content taken from ASSH website
additional information:
WORK RELATED CARPAL TUNNEL IN MASSACHUSETTS fact sheet
HAND SURGERY AND PREVIOUS MASTECTOMY
ENDOSCOPIC SINGLE PORTAL CARPAL TUNNEL SURGERY
CARPAL TUNNEL RELEASE VS. SPLINTING
CARPAL TUNNEL RELEASE QUESTIONS AND ANSWERS FROM WWLP WEBSITE
CARPAL TUNNEL ENDOSCOPIC or "small incision" FAQ
Single-Portal Endoscopic Carpal Tunnel Release Compared with Open Release
FOSAMAX AND CARPAL TUNNEL SYNDROME
WIKIPEDIA: ENDOSCOPIC CARPAL TUNNEL RELEASE